Sweat & detox Blood, urine and sweat comparison · 2012

Plastic-related chemicals were found in sweat

Phthalates and some breakdown products appeared in sweat. Their concentrations differed from urine, without measuring total removal from the body.

Worth knowing: The same BUS participants also appear in the BPA, PCB/PFAS and flame-retardant articles. These are not independent replications.

The short version

The BUS study tested blood, urine and sweat for phthalates, chemicals used in plastics and other products. Some appeared in sweat even when absent from blood samples. For one breakdown product, MEHP, the median sweat-to-urine concentration ratio was 4.6 among 17 matched participants. That is a concentration comparison, not evidence that sweating removed 4.6 times as much. Other breakdown products appeared mainly or exclusively in urine.

Keep in mind

Concentration ratios do not account for the different volumes of sweat and urine produced.

What they found

MEHP was detected in all available blood, urine and sweat samples. Its median sweat-to-urine ratio was 4.6. Some other metabolites were detected in urine but not sweat.

What this means for your practice

Different chemicals leave the body differently. A result for one phthalate does not establish general detoxification.

Methods and limitations

What the researchers did

Twenty adults provided samples; usable amounts differed by fluid. Seventeen had matched data for three metabolites.

How much can this tell us?

This supports excretion of particular compounds through sweat. It does not measure a lasting fall in body stores or a health benefit.

What makes it useful

  • Matched fluid measurements

What limits it

  • One small shared sample
  • No long-term intervention
  • Different compounds behave differently
Where this study fits

Where this study fits

We score claims, not single studies. This one is part of the evidence for:

From the same participant group as 3 other articles in The Study, so we count them as one group of people.

Read the original

Genuis SJ et al. Human Elimination of Phthalate Compounds: Blood, Urine, and Sweat (BUS) Study. The Scientific World Journal. 2012.

Read the original study

DOI 10.1100/2012/615068 · PubMed 23213291

Next reading

  • 20 participants

    Sweat & detox Blood, urine and sweat comparison · 2012

    BPA appeared in sweat, including when blood tests missed it

    A small study detected BPA in sweat from 16 of 20 adults. It did not track whether repeated sweating lowered the amount in their bodies.

    Same cohort as this article

  • 20 participants

    Sweat & detox Blood, urine and sweat comparison · 2013

    PCBs and PFAS gave different answers in sweat

    Some PCBs appeared in sweat. The common PFAS tested showed little or no excretion through sweat, even with raised blood levels.

    Same cohort as this article

All articles in The Study